L carnitine. L

Blázquez-Moraleja A, Sáenz-de-Santa María I, Chiara MD, Álvarez-Fernández D, García-Moreno I, Prieto-Montero R, Martínez-Martínez V, López Arbeloa I, Chiara JL L-Carnitine is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates
PMID: 34084361 Free PMC article

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Further research is warranted in order to evaluate the biochemical, pharmacological, and physiological determinants of the response to carnitine supplementation, as well as to determine the potential benefits of carnitine supplements in selected categories of individuals who do not have fatty acid oxidation defects.

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The aging eye and the role of L
Recent studies have started to shed light on the beneficial effects of L-carnitine when used in various clinical therapies
The aging eye and the role of L
While carnitine levels in human ocular tissue are unknown, animal studies indicate that carnitine is differentially distributed within the eye with the highest concentrations reported in the iris, ciliary body and the choroid-retina
The aging eye and the role of L
In patients with age-related macular degeneration AMD , acetyl-L-carnitine improved four parameters of visual function, including visual field mean defect, visual acuity, foveal sensitivity and ocular fundus alterations
The majority of ocular pathologies originate from a functional deterioration of intraocular tissues This age-related deterioration often occurs as a result of changes within the eye
Because L-carnitine and its esters help reduce oxidative stress, they have been proposed as a treatment for many conditions, i L-Carnitine can also be found in many foods, but red meats, such as beef and lamb, are the best choices for adding carnitine into the diet

The aging eye and the role of L

There is growing interest in the role of natural or synthetic compounds, such as carnitine, for blocking, or slowing, the progress of this deterioration.

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The aging eye and the role of L
L-carnitine and its derivatives are involved in numerous physiological reactions, including sugar aerobic metabolism, oxidative phosphorylation, fatty acid oxidation and osmosis
The aging eye and the role of L
Essentially, L-carnitine transports the chains of fatty acids into the mitochondrial matrix, thus allowing the cells to break down fat and get energy from the stored fat reserves
The aging eye and the role of L
For other conditions, such as fatigue or improving exercise performance, L-carnitine appears safe but does not seem to have a significant effect